This means that at all levels the desire will be turned inside out and all your intentions that you could direct to bestowal, love, and connection with the Creator will turn into egoistic qualities that will humiliate and subdue you.
On the material level, all of this appears on the skin because skin is Malchut, the outermost layer.
Torah, Deuteronomy 28:28: The Lord will strike you with insanity, with blindness, and with bewilderment.
Insanity is damage on the level of the head (Mocha).
Blindness means that you see and feel nothing; that is, you cannot choose correctly and make decisions.
Bewilderment is an inability to analyze what is happening to you. You lose yourself completely, like a person who has gone mad and doesn’t know where he is and who he is. However, even this state is often absent in a madman.
In other words, a person who wanted to ascend to a higher degree was unable to take this height and shattered into pieces. However, he had to master it because it was up to him.
From KabTV’s “Secrets of the Eternal Book” 12/7/16