Answer: If a person has a soul, then it can be in pain. And the soul is a quality of bestowal and love for one’s neighbor. Therefore, from the point of view of Kabbalah, pain in the soul is that I cannot realize my sincere and kind feelings toward others.
This can be likened to how parents want to do something good for their child, but they cannot because the child resists.
Question: What does a person mean when he says that his soul hurts?
Answer: An ordinary person does not have a soul! It is simply that when a person’s nervous system is stressed, the heart contracts as it pumps blood throughout the body. And people are used to saying their soul is in pain.
But this is not a soul. The soul is the quality of bestowal, and its pain is its inability to realize oneself in bestowal to others.
From the Kabbalah Lesson in Russian 8/20/17